A common question about the recent wave of psychedelic research is, “how do these mind-altering substances work in the brain to produce a rapid reduction of symptoms and long-lasting improvements for a variety of mental health disorders?” Beyond some scientifically well-founded hypotheses and pure speculation, we haven’t had enough experimental evidence on psychedelics to draw from to make any large claims about the mechanisms responsible for therapeutic response. MDMA and psilocybin, both showing promising results in clinical trials, are two very different drugs, in terms of how they make people feel and how they act in the brain. Is it possible there is a common mechanism in the brain underlying the therapeutic effects of all psychedelics? New findings published by Ly et al. in the […] Read More